生物医学工程系学术报告5.27（报告人： Dr. Ng Kee Woei）
发布时间: 2010-05-25 04:28:00
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北京大学工学院 生物医学工程系学术报告 |
报告一题目：Activities at the School of Materials Science and Engineering, NTU
报告二题目：Knitted PLGA Mesh as an Alternative Substrate for Tissue Engineering Skin
报告人 Dr. Ng Kee Woei
Assistant Professor at the School of Materials Science and Engineering,
Nanyang Technological University, Singapore
报告人简介
Dr Ng Kee Woei was a recipient of the A*STAR Graduate Scholarship in Singapore. A mechanical engineer by training, he completed his PhD at the Yong Loo Lin School of Medicine, National University of Singapore, in 2005. He worked on tissue engineering a skin equivalent for his PhD thesis, using combinations of primary human cells and biomaterials. He has also worked on a number of different projects on tissue engineering bone and cartilage using scaffolds made by rapid prototyping techniques. Dr Ng underwent postdoctoral training stints at the Institute of Molecular and Cell Biology and the Institute of Medical Biology, A*STAR. During that time, he worked on embryonic and epithelial stem cells, wound healing and keratin dynamics. Dr Ng is currently Assistant Professor at the School of Materials Science and Engineering, Nanyang Technological University, Singapore.
报告一内容摘要
The School of Materials Science and Engineering at the Nanyang Technological University is actively involved in research in the fields of biomaterials, nanomaterials, defence materials and alternative energy. Our research is often designed with the aim of translating basic science to real life applications. In this talk, I will briefly introduce some of the research activities in the school, with particular emphasis on research in the field of Biomaterials.
报告二内容摘要
Tissue engineered skin has become a clinical reality. However, despite a number of such products available today, autografts continue to be the gold standard in skin grafting. My PhD research was aimed at developing a novel technique of tissue engineering skin. It was hypothesized that assimilating weft-knitted PLGA meshes and fibroblast sheets will produce viable, ECM-rich dermal constructs that can alleviate problems of graft contraction in current techniques of skin tissue engineering. For this purpose, a weft-knitted, biodegradable poly(lactic-co-glycolic acid) mesh was fabricated as the matrix for dermal regeneration. Human dermal fibroblasts were cultured in this matrix to form a dermal equivalent, on which human keratinocytes were cultured to form a bi-layered skin construct. These skin constructs were transplanted onto full-thickness wounds in nude rats and were shown to support healing while resulting in wound contraction that was similar to autografts.
主持人：魏世诚 老师
时 间：5月27日（周四）下午2:00 & 2:45
地 点：力学楼434会议室
欢迎广大老师和学生参加！