工学院特邀报告暨生物医学工程系学术报告10.20
发布时间: 2009-10-15 10:28:00
北京大学工学院 Distinguished Lecture
特邀报告 
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Series
生物医学工程系
S1P regulates migration of mesenchymal stem cells that contribute to liver fibrosis
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报告人 Lingsong Li 教授
Chairman, Department of Cell Biology
Peking University School of Medicine
报告内容摘要：
Bone marrow-derived mesenchymal stem cells (MSCs) have been used for treating li ver disorders in different animal models. However, it has been noted recently th at MSCs may be involved in the liver fibrosis in human patients. Using green-col or MSCs isolated from GFP-transgenic mice, we confirm that MSCs indeed contribut e significantly to liver fibrosis, and find that sphingosine 1-phosphate (S1P) r egulates the migration of MSCs into the damaged liver. Moreover, we provide evid ence that the blocking of S1P signals significantly improves the condition of li ver fibrosis in mice.
主持人：葛子钢 特聘研究员
时 间：10月20日（周二）上午9:00
地 点：英杰交流中心第四会议室
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